The Future of Drug Cost Management: Smarter Data, Better Outcomes

Nov 5, 2025

Rising drug costs continue to pressure healthcare providers, payers, and long-term care (LTC) pharmacies alike. Yet, for most organizations, pharmacy spend remains opaque, spread across formularies, PBMs, and claims systems that don’t talk to one another.

At VistaRx, we believe drug cost management shouldn’t be complicated. With the right data infrastructure, organizations can move from reactive cost control to proactive, intelligent pharmacy management.

Understanding Drug Cost Management

Drug cost management is the practice of controlling total prescription spend through smarter purchasing, claims oversight, and rebate capture. It’s not just about negotiating better prices, it’s about ensuring every claim, formulary decision, and PBM contract aligns with both clinical and financial goals.

In long-term and post-acute care, this can be particularly challenging. Formularies must balance cost efficiency with regulatory compliance and patient outcomes. Facilities depend on LTC pharmacies and PBMs to ensure the right drugs are covered, billed, and reimbursed correctly.

That’s where visibility matters most. Without real-time insight into utilization, coverage gaps, or missed rebates, organizations lose both time and revenue.

The Role of the Formulary

A formulary isn’t just a list, it’s a strategic tool. Well-designed formularies guide prescribers toward clinically effective and cost-efficient therapies. Poorly managed ones lead to inconsistency, unnecessary expense, and compliance risk.

VistaRx’s expertise in Formulary Management brings structure and oversight to this process. By integrating with EHR and claims data, facilities can ensure that therapeutic interchanges and preferred-drug lists are aligned with coverage policies and real-world outcomes.

Effective formulary management doesn’t just reduce waste, it improves adherence and reimbursement accuracy across facilities.

PBMs and the Rebate Equation

Pharmacy Benefit Managers (PBMs) play a major role in drug pricing and reimbursement. According to the Kaiser Family Foundation, rebates negotiated by PBMs can exceed $200 billion annually across the U.S. drug market, with limited visibility for downstream providers or facilities.

For LTC operators and pharmacies, missed or miscalculated rebates directly impact net spend. VistaRx’s Focus platform automates rebate tracking and reconciliation, ensuring eligible dollars aren’t left on the table. Facilities can see which claims qualify for manufacturer or PBM rebates, monitor rebate status, and validate payments, all within a single dashboard.

Transparent PBM rebate management is essential for sustainable drug cost management and pharmacy operations, especially in value-based care environments.

Claims Adjudication: Accuracy in Real Time

Claims adjudication is the final checkpoint before reimbursement. Errors here—whether incorrect coverage data, duplicate fills, or missing eligibility—can cost thousands per month and distort a facility’s financial picture.

Clean Bill by VistaRx brings real-time adjudication and EHR integration to the forefront, preventing billing errors before they occur. Facilities can identify rejected claims instantly, resolve discrepancies, and ensure correct payer routing without relying on manual audits.

By connecting adjudication with formulary and rebate data, VistaRx helps clients achieve 8% lower net drug costs on average: proof that operational clarity drives measurable savings.

Beyond Technology: A Partnership Approach

Technology alone can’t solve the complexity of pharmacy data. It requires a partner that understands the healthcare industry and all parties involved: PBMs, payers, operators, and pharmacies. 

VistaRx’s Advocacy and Expertise services combine consulting, formulary design, and audit support to help clients adapt to changing reimbursement models. Our team works directly with payers, manufacturers, and PBMs to improve contract performance, benchmark spend, and identify new rebate opportunities.

The result? Fewer uncovered fills, higher rebate recovery, and clearer visibility across every claim.

Why Data Infrastructure Matters

SaaS solutions often add dashboards but not clarity. VistaRx was built as infrastructure—a foundation for all your pharmacy data. That distinction matters. Infrastructure platforms integrate with existing EHR, PBM, and claims systems to unify data and automate decision points that would otherwise require hours of manual work.

The result is not another tool, but an ecosystem: one where every fill, rebate, and formulary update connects seamlessly across your operation.

The Path Forward

Drug cost management will only grow more complex as reimbursement models evolve and regulatory oversight expands. CMS continues to tighten expectations for transparency, rebate disclosure, and prescription alignment under value-based care.

For LTC and post-acute providers, the path forward is clear:

  • Integrate data across systems.

  • Audit rebates and claims regularly.

  • Align formularies with financial and clinical goals.

  • Partner with technology built for healthcare, not generic SaaS.

VistaRx helps clients turn pharmacy data into actionable insight. Whether you’re a PBM seeking to improve adjudication accuracy or an LTC pharmacy aiming to recover missed rebates, we make drug cost management simpler, smarter, and more transparent.

Learn More

Founded in 2018, VistaRx (Vista) provides comprehensive pharmacy data capture and management solutions for a variety of entities in the pharmacy value chain. We utilize custom-coded technology, strategies, and partnerships to help our clients improve operations and reduce dependence on third-party vendors.

Sign Up for Vista Insights and Updates

Sign Up for Vista Insights and Updates

Sign Up for Vista Insights and Updates